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3' deoxyInosine

Return to Modified Bases Modifications

Historically, the first universal base employed was 2’-deoxyInosine (dI). DeoxyInosine is a naturally occurring base that, while not truly universal, is less destabilizing than mismatches involving the four standard bases. Hydrogen bond interactions between dI and dA, dG, dC and dT are weak and unequal, with the result that some base-pairing bias does exist with dI:dC > dI:dA > dI:dG > dI:dT. When present in a DNA template, deoxyInosine preferentially directs incorporation of dC in the growing nascent strand by DNA polymerase.

Scientific Details
MW:314.2
Mod Code:/3deoxyI/
Pricing Details
ProductPricingOrder
100 nmole DNA Oligo $19.00 SGD Add To Order
250 nmole DNA Oligo $23.00 SGD Add To Order
1 umole DNA Oligo $34.00 SGD Add To Order
2 µmole DNA Oligo $43.00 SGD Add To Order
5 umole DNA Oligo $77.00 SGD Add To Order
10 umole DNA Oligo $144.00 SGD Add To Order
100 nmole RNA Oligo $19.00 SGD Add To Order
250 nmole RNA Oligo $23.00 SGD Add To Order
1 umole RNA Oligo $34.00 SGD Add To Order
5 umole RNA Oligo $77.00 SGD Add To Order
10 umole RNA Oligo $144.00 SGD Add To Order
100 nmole DNA Plate Oligo $19.00 SGD Add To Order
250 nmole DNA Plate Oligo $23.00 SGD Add To Order
1 umole DNA Plate Oligo $34.00 SGD Add To Order
Structure
Structure