5-Methyl deoxyCytidine when substituted for dC will increase the Tm by as much as 0.5°C per insertion. In addition, the presence of 5-Methyl dC in CpG motifs can prevent or limit unwanted immune responses that otherwise occur if oligos are administered in vivo, which is of particular importance in antisense applications.

Scientific Details

MW:	303.2
Mod Code:	/3Me-dC/

Pricing Details

Product	Pricing	Order
100 nmole DNA Oligo	$124.00 SGD	Add To Order
250 nmole DNA Oligo	$155.00 SGD	Add To Order
1 umole DNA Oligo	$227.00 SGD	Add To Order
2 µmole DNA Oligo	$294.00 SGD	Add To Order
5 umole DNA Oligo	$520.00 SGD	Add To Order
10 umole DNA Oligo	$968.00 SGD	Add To Order
100 nmole RNA Oligo	$124.00 SGD	Add To Order
250 nmole RNA Oligo	$155.00 SGD	Add To Order
1 umole RNA Oligo	$227.00 SGD	Add To Order
5 umole RNA Oligo	$520.00 SGD	Add To Order
10 umole RNA Oligo	$968.00 SGD	Add To Order

Structure