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5' 5-Methyl dC

Return to Modified Bases Modifications

5-Methyl deoxyCytidine when substituted for dC will increase the Tm by as much as 0.5°C per insertion. In addition, the presence of 5-Methyl dC in CpG motifs can prevent or limit unwanted immune responses that otherwise occur if oligos are administered in vivo, which is of particular importance in antisense applications.

Scientific Details
MW:303.2
Mod Code:/5Me-dC/
Absorbance Max:277 nm
Extinction Coefficient
(At Absorbance max):		9000
Pricing Details
ProductPricingOrder
100 nmole DNA Oligo $94.00 SGD Add To Order
250 nmole DNA Oligo $113.00 SGD Add To Order
1 umole DNA Oligo $170.00 SGD Add To Order
2 µmole DNA Oligo $216.00 SGD Add To Order
5 umole DNA Oligo $386.00 SGD Add To Order
10 umole DNA Oligo $716.00 SGD Add To Order
100 nmole RNA Oligo $94.00 SGD Add To Order
250 nmole RNA Oligo $113.00 SGD Add To Order
1 umole RNA Oligo $170.00 SGD Add To Order
5 umole RNA Oligo $386.00 SGD Add To Order
10 umole RNA Oligo $716.00 SGD Add To Order
100 nmole DNA Plate Oligo $94.00 SGD Add To Order
250 nmole DNA Plate Oligo $113.00 SGD Add To Order
1 umole DNA Plate Oligo $170.00 SGD Add To Order
4 nmole Ultramer™ DNA Oligo $94.00 SGD Add To Order
4 nmole Ultramer™ DNA Plate Oligo $94.00 SGD Add To Order
20 nmole Ultramer™ DNA Oligo $113.00 SGD Add To Order
20 nmole Ultramer™ DNA Plate Oligo $113.00 SGD Add To Order
Structure
Structure