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CRISPR GUARD

CRISPR GUARD

Precise genome editing using CRISPR-Cas9 is a promising avenue for genetic disease research. However, there are a number of off-target editing issues to take into consideration.

In this webinar, Dr. Matthew Coelho discusses findings from his recent publication in Nature Communications, "CRISPR GUARD protects off-target sites from Cas9 nuclease activity using short guide RNAs."

Attendees will learn more about:

  1. The utility of CRISPR Guide RNA Assisted Reduction of Damage (GUARD) as a method for protecting off-targets sites by co-delivery of short guide RNAs directed against off-target loci by competition with the on-target guide RNA.
  2. Project design rules and the versatility of this method for in vitro studies and high-throughput screening.

Published on: August 03, 2022

Categories:
CRISPR genome editing Webinar

*RUO—For research use only. Not for use in diagnostic procedures. Unless otherwise agreed to in writing, IDT does not intend for these products to be used in clinical applications and does not warrant their fitness or suitability for any clinical diagnostic use. Purchaser is solely responsible for all decisions regarding the use of these products and any associated regulatory or legal obligations.