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DTSTART;VALUE=DATE:20210101
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DESCRIPTION:CRISPR systems enable targeted editing in a wide variety of org
 anisms by introducing single- or double-strand breaks (DSBs) to DNA\, whic
 h can be leveraged to introduce genomic changes. However\, unintended DSBs
  can occur off-target at genomic loci with partial complementarity to CRIS
 PR-Cas guide RNA (gRNA) sequences\, which can result in genotype/phenotype
  changes in the edited cells. Genome editing at on- and off-target sites c
 an be quantified with multiplexed targeted next-generation sequencing (NGS
 ) but requires bioinformatics expertise to analyze. Here we present the rh
 AmpSeq CRISPR Analysis System as a streamlined end-to-end solution for des
 igning assays\, generating sequencing libraries\, and analyzing NGS data f
 or quantifying CRISPR on- and off-target editing effects without the need 
 for bioinformatics experience.\nObjectives\n\n    Learn how rhAmpSeq CRISP
 R Analysis System can help you streamline your CRISPR genome editing analy
 sis\n    Learn how to simultaneously quantify intended edits and evaluate 
 off-target modifications with accuracy\n    Learn about reducing off-targe
 t effects without compromising potency\n
DTEND:20210331T000000Z
DTSTAMP:20221221T005835Z
DTSTART:20210331T000000Z
LOCATION:Virtual
SEQUENCE:0
SUMMARY:The rhAmpSeq™ CRISPR Analysis System—An end-to-end solution for gen
 ome editing quantification
UID:RFCALITEM638071811152061935
X-ALT-DESC;FMTTYPE=text/html:<p>CRISPR systems enable targeted editing in a
  wide variety of organisms by introducing single- or double-strand breaks 
 (DSBs) to DNA\, which can be leveraged to introduce genomic changes. Howev
 er\, unintended DSBs can occur off-target at genomic loci with partial com
 plementarity to CRISPR-Cas guide RNA (gRNA) sequences\, which can result i
 n genotype/phenotype changes in the edited cells. Genome editing at on- an
 d off-target sites can be quantified with multiplexed targeted next-genera
 tion sequencing (NGS) but requires bioinformatics expertise to analyze. He
 re we present the rhAmpSeq CRISPR Analysis System as a streamlined end-to-
 end solution for designing assays\, generating sequencing libraries\, and 
 analyzing NGS data for quantifying CRISPR on- and off-target editing effec
 ts without the need for bioinformatics experience.</p>\n<h3>Objectives</h3
 >\n<ul class="list">\n    <li>Learn how rhAmpSeq CRISPR Analysis System ca
 n help you streamline your CRISPR genome editing analysis</li>\n    <li>Le
 arn how to simultaneously quantify intended edits and evaluate off-target 
 modifications with accuracy</li>\n    <li>Learn about reducing off-target 
 effects without compromising potency</li>\n</ul>
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